You’ve tried all the low-carb, no-carb, point-counting, intermittent-fasting influencer diets, yet somehow, the scale refuses to budge.
So, you know it’s not just “lack of willpower.” For folks battling stubborn weight, GLP-1 meds like Ozempic® or Mounjaro® can change the game, but only if you work with a clinic that knows what it’s doing and won’t rob you blind.Today, we’re digging into Sesame Care, a telehealth platform that might help you finally get medical support for weight loss. Does it deliver, or is it just another website cashing in on the GLP-1 buzz?
📋Our Score: 4/5
| Category | Rating |
|---|---|
| Results | ★★★★☆ |
| Ease of use | ★★★★★ |
| Medical expertise | ★★★★☆ |
| Cost & transparency | ★★★★★ |
| Customer support | ★★★☆☆ |
How we rate: Our score reflects the latest available data, customer feedback, clinical transparency, and ease of patient onboarding. See our review methodology here.
| Pros | Cons |
|---|---|
| ✅ Transparent pricing with no hidden fees | ❌ No dedicated nutrition coaching or meal-planning programs |
| ✅ Same-day consultations | ❌ Buggy mobile app |
| ✅ Video visits and unlimited chat | ❌ Lab work not covered in AZ, HI, ND, NJ, NY, OK, RI, SD, WY |
| ✅ No insurance required | ❌ Variable provider quality |
| ✅ Insured patients welcome | |
| ✅ Wide range of weight-loss medications | |
| ✅ Freedom to choose your provider | |
| ✅ Personalized treatment | |
| ✅ Choose any time that works for you | |
| ✅ Video consultations with board-certified providers |
🚨 Wait! There’s a Better Option
Sesame Care’s weight-loss offering can feel limited for many patients, with no dedicated nutrition coaching, a buggy mobile app, labs not covered in several states, and uneven provider quality.
If you want stronger support and clearer coverage, compare the top online GLP-1 providers.
- Nutrition Coaching Included: Structured meal planning and habit support.
- Reliable App Experience: Stable, user-friendly tools that work when you need them.
- Lab Coverage Clarity: Included labs or upfront, state-specific pricing.
- Consistently Vetted Providers: High standards for experience and patient care.
What Is Sesame Care?
Sesame Care started as a healthcare marketplace where you could book appointments with doctors without insurance hassles. Now it’s jumped into the weight-loss game with the “Success by Sesame” weight-loss program, and honestly, it’s bringing more medication options to the table than almost any other clinic out there.
Unlike the typical one-size-fits-all approach, where everyone gets the same compounded semaglutide, this program offers an impressive 14 different weight-loss medications, from brand-name GLP-1s like Wegovy® and Zepbound® to alternatives like Contrave and metformin.
What makes Sesame different from other weight-loss clinics is its marketplace approach. Instead of being assigned a random provider, you get to browse and choose your own doctor based on their specialty, experience, and patient reviews.
The service operates completely online through telehealth visits, unlimited messaging, and home delivery of medications.
How Does Sesame Care Work?
Most people think getting GLP-1 medications is complicated, but Sesame’s process is refreshingly straightforward.
Step 1: Initial Assessment
You’ll fill out a thorough questionnaire covering your medical history, family history, current medications, weight-loss goals, and factors that influence your overall health. This goes way beyond basic BMI calculations to understand your complete health picture.
Step 2: Consultation and Labs
Before your consultation, you get to choose from Sesame’s network of licensed healthcare providers based on reviews, ratings, and specialties, rather than being randomly assigned.
During your initial video consultation (typically within 24 hours), your provider reviews your intake information and determines if weight-loss treatment fits your specific situation.
If your provider recommends proceeding, you’ll complete necessary lab work through Quest Diagnostics (over 1,500 locations nationwide) to assess key health markers.
Step 3: Treatment
Once your lab results are processed, your provider will create a personalized treatment plan from 14 available medication options.
Your prescribed medication arrives via home delivery for convenience. But you can have it sent to a pharmacy for you to pick up if that’s your preference.
You’ll also receive detailed guidance on diet, exercise, and lifestyle changes along with your prescription.
Step 4: Regular Monitoring and Adjustments
Throughout treatment, you have unlimited messaging access to your provider for questions, side effect management, and dose adjustments. Face-to-face video consultations happen as needed, with close monitoring for issues like nausea or other medication responses. They’ll also continue to advise you on necessary changes to diet, exercise, and lifestyle habits.
Treatment Options at Sesame Care
Success by Sesame offers one of the most comprehensive medication selections I’ve seen among online weight-loss clinics. With 14 different options, your provider can truly customize treatment based on your specific needs, side effect tolerance, and medical history.
Weekly GLP-1 Injections (Most Effective for Weight Loss)
- Zepbound (tirzepatide): FDA-approved dual GLP-1/GIP receptor agonist that targets multiple hormones controlling blood sugar and appetite; 15%–20% potential weight loss
- Wegovy (semaglutide): FDA-approved GLP-1 receptor agonist specifically designed for weight management; 10%–15% potential weight loss
- Mounjaro (tirzepatide): originally FDA-approved for type 2 diabetes but prescribed off-label for weight loss; 15%–20% potential weight loss
- Ozempic (semaglutide): FDA-approved for type 2 diabetes management but commonly prescribed off-label for weight loss; 10%–15% potential weight loss
- Trulicity® (dulaglutide)*: GLP-1 receptor agonist approved for type 2 diabetes treatment; when prescribed off-label, 5%–10% potential weight loss
Daily GLP-1 Injections (Flexible Dosing):
- Saxenda® (liraglutide)*: FDA-approved specifically for weight management in adults and adolescents with obesity to control appetite; 5%–10% potential weight loss
- Victoza® (liraglutide)*: FDA-approved for type 2 diabetes management but prescribed off-label for weight loss; 5%–10% potential weight loss
- Liraglutide: FDA-approved generic version of Victoza offering the same appetite-suppressing benefits at a potentially lower cost; 5%–10% potential weight loss
Twice-Daily Injections:
- Byetta® (exenatide): one of the first GLP-1 medications, FDA-approved for type 2 diabetes but used off-label for weight management
Oral Medications:
- Rybelsus® (oral semaglutide): the first oral GLP-1 medication, FDA-approved for type 2 diabetes; must be taken on an empty stomach; 10%–15% potential weight loss
- Contrave® (bupropion/naltrexone): FDA-approved combination medication for chronic weight management; combines an antidepressant with an addiction treatment medication to reduce food cravings and emotional eating
- Metformin: classic diabetes medication that helps with insulin sensitivity and modest weight loss; often used as a first-line treatment or combined with other medications for enhanced results
- Topiramate: originally developed for seizures and migraines but prescribed off-label for weight loss; often combined with other therapies to suppress appetite and support weight management
It’s important to remember that none of these medications is magic. They must all be combined with nutrition and lifestyle changes to achieve your long-term weight-loss goals.
* Due to national shortages, Saxenda, Victoza, and Trulicity have limited availability through 2025.
Sesame Care Pricing: Simple Structure, Extensive Options
Sesame costs just $99 per month for comprehensive medical management, a low price considering it provides more medication variety than practically any other online clinic.
Monthly subscription:
Costs $99 every 28 days (aligns with medication cycles).
Brand-name GLP-1 prices:
- Wegovy: $299 first month (new patients), then $499/month without insurance; $25/month with insurance
- Zepbound prefilled injection pen: $1,086/month without insurance; $25/month with insurance
- Zepbound vials with separate syringe you have to measure and load yourself: $349/month (self-pay only, no insurance accepted)
- Mounjaro: $1,079/month without insurance; $25/month with insurance
- Ozempic: $998/month without insurance; $25/month with insurance
- Saxenda: $1,349/month without insurance; $25/month with insurance
Daily injection prices:
- Victoza: $544/month without insurance; $25/month with insurance
- Liraglutide (generic for Victoza): $470/month without insurance; $25/month with insurance
- Byetta: $1,006/month without insurance; $25/month with insurance
Oral medication prices:
- Rybelsus: $998/month without insurance; $25/month with insurance
- Contrave: $662/month without insurance; $25/month with insurance
- Metformin: $34/month without insurance; often $0 with insurance
- Topiramate: $155/month without insurance; often $0 with insurance
Weekly alternative prices:
- Trulicity: $987/month without insurance; $25/month with insurance
Sesame does not bill your insurance for provider visits or its weight-loss subscription, only for medication.
You pay the flat fee, no deductibles, no surprise claims, no headache. That’s how it keeps costs transparent.
However, if you have insurance, Sesame’s providers can assist with prior authorization paperwork for GLP‑1 medications, which could bring your out‑of‑pocket med price down to as little as $25/month.
But that’s only for meds. Sesame’s clinical program remains cash‑paid regardless of your insurance status.
You can use your HSA or FSA card at checkout for visits, labs, or a Sesame subscription. If the card doesn’t work, you can pay out of pocket and submit the receipt for reimbursement. Just note: medication coverage depends on your plan and diagnosis.
What’s Included in Sesame Care’s Monthly Subscription?
The $99 membership fee at Sesame gets you everything you need to get started:
- Initial medical consultation and comprehensive assessment
- Provider choice based on reviews and ratings
- Lab testing through Quest Diagnostics (most states)
- Personalized treatment plan from 14 medication options
- Insurance pre-authorization assistance for medications
- Unlimited provider messaging and support
- Face-to-face video consultations as needed
- Basic diet, exercise, and lifestyle guidance from providers
- Home medication delivery coordination
- HSA/FSA payment eligibility
What’s Not Included in the Subscription?
Sesame keeps things medically focused, which means skipping extras some people expect:
- Medication costs (separate from subscription)
- Dedicated nutrition coaching or meal-planning programs
- Behavioral therapy for emotional eating patterns
- Fitness programming or structured exercise plans
- Lab costs in AZ, HI, ND, NJ, NY, OK, RI, SD, WY
- 24/7 customer support availability
- Guaranteed medication availability during shortages
Lab Testing: What Gets Measured and Why It Matters
Lab testing is included in your monthly program fee and processed through Quest Diagnostics’ 1,500+ locations nationwide. However, lab costs aren’t covered if you live in Arizona, Hawaii, North Dakota, New Jersey, New York, Oklahoma, Rhode Island, South Dakota, or Wyoming.
Initial baseline testing covers all important health markers:
- A1C (Hemoglobin A1C)
- Fasting glucose
- Lipid panel
- Liver enzymes (ALT, AST)
- Kidney function (creatinine, BUN)
- Thyroid function (TSH)
- Complete blood count (CBC)
Most patients complete initial labs before starting treatment, then follow-up testing every 3–6 months, depending on their provider’s assessment and treatment response.
You can schedule appointments at Quest locations or walk in, depending on availability. Results are reviewed by your provider, who explains findings through your unlimited messaging access.
🎯 Who Should Use Sesame Care?
Sesame’s Success by the Sesame program works best for specific types of people rather than trying to be everything to everyone.
➡️ Those who want the freedom to choose from extensive medication options
Sesame offers 14 different weight-loss medications compared to 2–4 at most competitors. This level of choice is rare in telehealth weight loss.
➡️ Insured patients
If you have insurance, providers handle pre-authorization paperwork to potentially reduce brand-name medication costs from $1,000+ monthly to just $25.
➡️ Choosy patients who want to pick their provider
Unlike clinics that randomly assign providers, Sesame lets you review ratings and specialties before selecting your healthcare professional. This provider relationship continues throughout treatment with unlimited messaging and video consultations as needed.
➡️ Consumers sick of hidden prices and upsells
At $99 every 28 days, you know exactly what clinical care costs. Medication pricing is separate but transparent, and since Sesame isn’t a pharmacy, it has no financial incentive to push expensive options over cheaper alternatives.
➡️ Independent patients not interested in hand-holding
Sesame provides excellent medical management, basic diet and lifestyle guidance, and unlimited messaging support, but you’re responsible for implementing lifestyle changes. Perfect for people who need medication help but can handle their own diet and exercise modifications.
🚫 Who Is Sesame Care Not For?
Skip Sesame if you need comprehensive lifestyle programming beyond basic medical guidance. While providers offer diet and exercise advice, there’s no structured nutrition coaching, meal planning, or behavioral therapy for emotional eating patterns.
For personalized weight-loss plans and app-based progress tracking, try Ro’s Body Program instead.
You’ll want to look elsewhere if you’re not comfortable with the separate subscription and medication billing structure. Some people prefer all-inclusive pricing where everything is bundled, rather than managing two different costs monthly (or every 28 days).
This program also isn’t ideal if you live in one of the nine states where lab costs aren’t included. Additional lab fees could make the total cost less predictable.
Finally, if you prefer monthly billing cycles rather than 28-day cycles, Sesame’s alignment with medication supply schedules might feel inconvenient for budgeting purposes.
How Does Sesame Care Compare to Other Clinics?
When weighing Sesame against competitors, the pricing transparency and provider choice stand out, but limited treatment options might feel restrictive.
Swipe to scroll the table below →
| Clinic | Best for | Monthly cost | Treatment types | Lab testing | Add-ons | Insurance |
|---|---|---|---|---|---|---|
| Sesame Care | Provider choice & wide variety of medication | $99 + meds | 14 different brand-name & generic options | Included but limited eligibility | Minimal | Yes (meds only) |
| Shed | Transparent, affordable pricing and results driven care | Starts at $199/mo | Wegovy; Zepbound; compounded GLP-1s | Not required | Optional coaching ($49.99) | No |
| Remedy Meds | Fast, inclusive access with flat pricing | from $299/mo | Compounded semaglutide; tirzepatide (brand-name options available) | Included | None | No |
| Ro Body Program | Comprehensive care with insurance support | $145/mo (meds not included) | Brand name + compounded | Included | 1:1 coaching; holistic curriculum; app tracking | Yes (meds only) |
| Weight Watchers | Combination of medication and behavioral support | $74/mo with 12-month commitment (meds not included) | Brand-name injectables and oral meds | Not included | 1:1 coaching; app tracking; optional workshops (from $22/mo) | Yes (meds only) |
| Calibrate | Structured, long-term support | $199/mo with 3-month commitment (meds not included) | Ozempic; Wegovy; Mounjaro; Zepbound; Saxenda; Trulicity®; Rybelsus | Not included | Lifestyle coaching | Yes (meds only) |
Real User Experience With Sesame Care
Sesame has 2,680 five-star reviews out of 3,235 on Trustpilot. Users consistently praise the platform for transparent pricing, which is hard to find these days, truly, as well as provider choice and efficient service delivery. Overall, Sesame has a four-star rating out of 3,187 reviews.
Users consistently praise the platform for transparent pricing (again, a unicorn), provider choice, and efficient service delivery. Complaints typically focus on customer support response times for billing or technical issues rather than clinical care quality.
Final Verdict
If you’re looking for a flexible, affordable GLP-1 clinic with a wide medication range, Sesame is a top-tier choice. The Success by Sesame program combines affordability with real clinical care, not just prescriptions. Unlike some clinics that force you into one medication or tack on surprise fees, Sesame offers transparency, provider choice, and legitimate long-term support.
With fair pricing, real medical oversight, and unmatched medication variety, Sesame sets a new standard for online weight-loss clinics.
FAQs
How much does Sesame Care’s weight-loss program cost monthly?
The Success by Sesame program costs $99 per month for comprehensive medical care, billed every 28 days to align with medication schedules. Medication costs are separate and range from as low as $34/month for metformin to over $1,000/month for premium brand-name options without insurance. With insurance coverage, most patients pay just $25/month for brand-name medications. The program includes unlimited provider messaging, lab testing, consultations, and insurance assistance.
What weight-loss medications does Sesame Care offer?
Sesame Care offers 14 different weight-loss medications, the most comprehensive selection among online clinics. Options include weekly GLP-1 injections like Wegovy, Zepbound, and Mounjaro; daily options like Saxenda; oral medications like Rybelsus and Contrave; plus budget-friendly generic alternatives like metformin and topiramate. Your provider recommends the best option based on your health profile, goals, and budget rather than pushing specific medications.
Does Sesame Care accept insurance for weight-loss medications?
Yes, Sesame Care provides insurance assistance, and your provider handles pre-authorization paperwork to reduce medication costs. Many patients with private insurance pay just $25/month for brand-name medications. However, Medicare and Medicaid typically don’t cover GLP-1 medications for weight loss. The $99 monthly program fee is always cash-pay and not covered by insurance, keeping pricing transparent without surprise bills.
Can I choose my own provider with Sesame Care?
You can absolutely choose your own provider with Sesame Care. Sesame’s marketplace approach lets you browse healthcare provider profiles, read patient reviews and ratings, and select someone based on their specialties and experience. You can see their credentials, treatment approaches, and patient feedback before making your choice. This provider selection process is included in your monthly program fee and helps ensure better treatment outcomes through proper provider-patient matching.
Are lab tests included in Sesame Care’s program?
Lab testing is included in your $99 monthly subscription and processed through Quest Diagnostics’ 1,500+ locations nationwide. However, lab costs aren’t covered if you live in Arizona, Hawaii, North Dakota, New Jersey, New York, Oklahoma, Rhode Island, South Dakota, or Wyoming. Your provider orders appropriate tests based on your health needs, and you can schedule appointments or walk in at Quest locations for convenience.
Disclaimer: This review is for informational purposes only and does not constitute medical advice. Always consult a licensed healthcare provider before starting or changing any weight loss treatment plan.
Recent Updates
- November 21, 2025: Changed the price of Shed’s optional coaching program from $70 to $49.99. Added Wegovy and Zepbound to Shed’s available treatments while removing Ozempic and Mounjaro.
