I woke up exhausted. Again. Despite 8 hours of sleep, I felt like I’d been hit by a truck.
The worst part? This wasn’t just tiredness. My libido had disappeared, my gym progress had flatlined for months, and the stubborn belly fat wouldn’t budge no matter what I tried.
Sound familiar?
I started looking at low testosterone levels as the problem which led me to twenty different providers, hours of YouTube videos, and multiple labs and consultations.
What I discovered shocked me: the difference between the best and worst clinics isn’t just price—it’s potentially years of your hormonal health.
I’ve personally gone with FountainTRT because I respect and, more importantly, trust Dr. Doron Stember and the team he’s built over there.
But depending on your symptoms and goals, one of three other top clinics might be better for you.
Here’s my no-BS breakdown of the best online TRT clinics available right now.
| Notes: Online TRT clinics must comply with state and federal regulations regarding telemedicine and prescription medication. TRT must be administered under the close supervision of a licensed physician. |
1. FountainTRT
As mentioned above, FountainTRT is the best online TRT clinic and the product I personally use.
Pros & Cons
| Pros | Cons |
| ✔ Super smooth and seamless process with consistent and clear communication ✔ 24/7 communication via text messaging ✔ Doctors who live and breathe TRT and hormone replacement therapy instead of a GP who knows very little about this stuff | ✘ Not available in every state ✘ More expensive than a prescription |
The Process and My Experience
The first step is to complete Fountain’s online quiz to see if you qualify: https://fountain.net/trt
My experience: The quiz takes five minutes and is super quick and easy. The only bad thing is FountainTRT doesn’t work with every state because everything is done online and each state has different telemedicine laws. The only way to find out if it’s available in your state is to take the online quiz.
If Fountain can’t work with you, proceed to option two below (Defy Medical).
If you do qualify, once you complete the online quiz you will pay for the initial lab (cost is $35).
Shortly after your payment, support will text you to set up a lab appointment to get blood drawn. LabCorp is the only option, and entering your zip code will determine if there’s one near you.
My experience: Communication was awesome with FountainTRT. I got an appointment set up the same week and I actually love just being able to communicate via text 24/7.
Going into LabCorp was super easy. Took less than ten minutes. Checked in, waited three minutes, got blood drawn (I didn’t have to bring anything in since the paperwork was all online), and left.
Appointment was at 9:45 and I was out by 9:54.
Six days after doing my labs, I got a text from FountainTRT stating they had my results and asking me to schedule a virtual consultation with one of their doctors. They texted me on a Thursday and had openings pretty much every day.
To view my results I had to download a third-party app called Akute Health. I absolutely hate all the dang apps I have to download for services these days, but to be fair, the app was simple and easy to use.
I talked with Dr. Doron Stember the following Tuesday and we reviewed my labs (normal total testosterone levels but low free testosterone levels) together.
My experience: I thoroughly enjoyed and appreciated my consultation with Dr. Doron Stember. We talked through the concerns I had (increased red blood cell count and decreased sperm count) and figured out the right option for me.
Treatment Options
Since I was a candidate for TRT, Dr. Stember went ahead and prescribed me medicine. Patients choose one of three protocols:
- TRT injectables
- Testosterone cream
- Enclomiphene (oral tablet)
Since I plan on having kids in a few years, I went with Enclomiphene because it doesn’t lower sperm count.
If I were older, TRT injectables would have been a better option, but that wasn’t the best use case for me.
Pricing
FountainTRT has two main pricing options, which include everything no matter what protocol you choose.
- One-year package: $166 every four weeks
- Quarterly package: $199 every four weeks
It’s a bit expensive, but this includes everything: shipping, taxes, future lab tests, etc. They don’t try and sneak in any other fees, which I appreciate.
Again, it’s a bit expensive, but as someone who is self-employed, it costs 3x that just to see my damn doctor (who doesn’t even understand TRT). I’m happy with these prices.
Overall
It took me two weeks, start to finish, to get a prescription from FountainTRT. Started on October 28th and had a consultation and prescription by November 11th. This could have been done even quicker, but I had to wait a bit for labs and consult because of other time commitments.
Since going on Enclomiphene, my total testosterone has gone from 519 to 1,177.
But what’s more important is my free testosterone (which was the issue) has gone from 7.2 to 54.38.
These numbers are a bit high, but I’m working with Dr. Stember to monitor all other important biometrics, like my RBC, WBC, MCV, MCHC, etc.
Again, I love FountainTRT. Getting my numbers up has been a game changer for me in more ways than I can count. Mental clarity, weight loss, muscle gain, improved sex drive, you name it.
You’ll be in good hands with the team over there.
See if you qualify >>2. Defy Medical
Defy Medical is a well-established telemedicine provider specializing in hormone therapy, including TRT. Its approach is highly personalized, with an emphasis on comprehensive lab testing and physician oversight. Unlike some subscription-based services, Defy Medical offers customized treatment plans tailored to individual hormone levels and health needs.
Pros & Cons
| Pros | Cons |
| ✔ Extensive lab testing and in-depth medical evaluations ✔ Variety of treatment options, including injections, creams, and compounded medications ✔ Physicians who specialize in men’s hormone health and longevity | ✘ Higher initial consultation fees than some competitors (~$250) ✘ Varied monthly costs based on treatment needs |
Treatment Options
Defy Medical provides testosterone injections, topical creams, and compounded medications. It also offers additional therapies, like human chorionic gonadotropin (hCG) and aromatase inhibitors to optimize hormone balance.
Who Is Defy Medical Best For?
Defy Medical is ideal for men seeking a customized, physician-guided TRT experience. If you want a long-term, health-focused approach, rather than just a quick prescription, this clinic is a great option.
Cost With and Without Insurance
- With insurance: Insurance may cover some lab testing, but TRT treatments are typically self-pay.
- Without insurance: Initial consultation is ~$250, and monthly treatment costs range from $150–$250, depending on the prescribed medications.
Additional Information
- Stage of low testosterone treated: All stages of low testosterone, including early decline and severe deficiency.
- Age of men treated: Typically ages 30+ but depends on medical evaluation.
- Insurance coverage: Limited—some lab testing may be covered, but most treatment costs are out-of-pocket.
3. Henry Meds
Henry Meds takes a subscription-based approach to TRT, making the process simple, affordable, and completely online. With no in-person visits required, it offers an easy way for men to start treatment without long wait times.
Pros & Cons
| Pros | Cons |
| ✔ Flat-rate pricing (~$99/month), which includes consultations, labs, and prescriptions ✔ No hidden fees—medications delivered directly to your door ✔ Fully online process, including doctor consultations | ✘ Limited flexibility—fewer medication options compared to specialty clinics ✘ Limited additional hormone therapies (e.g., hCG, DHEA) |
Treatment Options
Henry Meds focuses on standard TRT therapy, primarily using testosterone injections shipped directly to patients.
Who Is Henry Meds Best For?
This clinic is great for men who want a simple, hassle-free TRT option with predictable pricing. If you prefer affordability and convenience over a highly customized plan, Henry Meds is a strong choice.
Cost With and Without Insurance
- With insurance: Henry Meds does not accept insurance but offers affordable cash-pay pricing.
- Without insurance: Flat $99/month, including doctor visits, labs, and medications.
Additional Information
- Stage of low testosterone treated: Primarily early to mid-stage testosterone decline.
- Age of men treated: Typically ages 30–60.
- Insurance coverage: No—Henry Meds operates on a direct-to-consumer cash-pay model.
4. TRT Nation
TRT Nation is known for fast, affordable testosterone therapy with a straightforward approval process. It partners with compounding pharmacies to provide low-cost, high-quality medications.
Pros & Cons
| Pros | Cons |
| ✔ Competitive pricing (~$100–$150/month) ✔ Quick prescription approvals and fast shipping ✔ Customized compounded testosterone treatments | ✘ Fewer support resources than full-service clinics ✘ Less focus on overall wellness beyond TRT |
Treatment Options
TRT Nation provides testosterone injections and compounded formulations, with options to add hCG or estrogen blockers if needed.
Who Is TRT Nation Best For?
TRT Nation is a great choice for men looking for low-cost, fast-access TRT. If you want affordable, high-quality testosterone therapy without unnecessary extras, this clinic delivers.
Cost With and Without Insurance
- With insurance: Not accepted—TRT Nation is a self-pay service.
- Without insurance: Costs range from $100–$150/month, including prescriptions.
Additional Information
- Stage of low testosterone treated: Best for mid to late-stage testosterone decline.
- Age of men treated: 30+, depending on individual symptoms and lab results.
- Insurance coverage: No—TRT Nation operates on a cash-pay basis.
TRT Clinic Comparison Table
Here’s a handy table that compares key aspects of these four online TRT clinics:
| Defy Medical | Henry | TRT Nation | FountainTRT | |
| Best for | Personalized, long-term care | Budget-friendly & convenient TRT | Affordable, fast access to treatment | Vast majority of people |
| Consultation fee | ~$250 | $0 | Low cost (~$100) | $0 |
| Monthly cost | ~$150–$250 | ~$99 | ~$100–$150 | $166–$199 |
| Lab testing | Required, full panel | Included in subscription | Required, affordable | Required, $35 |
| Treatment type | Customized TRT & HRT | Standardized TRT | Injectable TRT | Injectable, cream, oral tablet |
| Support & monitoring | Extensive | Moderate | Limited | Extensive |
| Prescription process | Physician-guided, tailored | Simple online process | Quick approval | Physician-guided, tailored |
Each of these clinics has its strengths, and the right choice depends on your budget, treatment preferences, and need for medical oversight.
- If you want a comprehensive and highly personalized approach, FountainTRT is the best option, but if it’s not available in your state, Defy Medical is a good alternative.
- For affordable and convenient TRT, Henry Meds provides a streamlined experience.
- TRT Nation is ideal for those seeking quick, cost-effective access to testosterone therapy.
Why TRT Is Good for Low Testosterone Symptoms
Testosterone plays a huge role in a man’s overall health. When your levels drop, you might notice changes that affect your everyday life. TRT is a treatment that helps replace testosterone when your body isn’t producing enough. Here’s why many men consider TRT:
- Boosts energy and vitality: Testosterone is key for maintaining energy. When levels drop, you might feel fatigued, and TRT can help revive that spark.
- Improves muscle mass and strength: Testosterone contributes to building muscle. TRT can help you regain strength and improve overall fitness. (Citation)
- Can enhance mood and cognitive function: Low testosterone can lead to mood swings, irritability, and difficulty concentrating. TRT helps stabilize mood and mental clarity in some men (it can also cause mood swings and irritability in others).
- Supports bone health: Testosterone also helps keep bones strong. TRT can reduce the risk of bone loss as you age, though it shouldn’t be considered the primary line of defense for osteoporosis. (Citation)
- Increases libido and sexual performance: One of the more talked-about benefits is improvement in sexual desire and performance. (Citation)
While TRT can improve energy, muscle mass, mood, and libido, the extent of these benefits varies—TRT is not a panacea.
For many men, supplementing your body’s natural testosterone with TRT can help you feel more like your younger self, with improved energy, strength, and overall well-being.
Common Symptoms of Low Testosterone
Knowing the signs of low testosterone is important, so you can decide if TRT might be right for you:
- Low energy: Feeling unusually tired, even after a good night’s sleep
- Decreased muscle mass: A noticeable drop in muscle strength and size
- Increased body fat: Particularly around the abdomen, even if your diet hasn’t changed
- Mood changes: Experiencing mood swings, irritability, or even mild depression
- Reduced libido: A lower sex drive than you’ve been accustomed to
- Cognitive challenges: Issues with memory, focus, or decision-making
Recognizing TRT symptoms early on can help you decide if it’s time to talk to a healthcare provider about TRT. When considering your symptoms, it’s important to note that they can also be caused by other conditions. Before beginning TRT, you should get blood tests to confirm low testosterone levels.
The Science Behind TRT
Understanding the science behind testosterone replacement therapy can help you make a more informed decision. Here’s a simple breakdown of what TRT is and how it works, explained in a way that’s easy to grasp.
What Is TRT?
Testosterone is a hormone that plays a critical role in many body functions:
- Muscle and bone health: It helps build and maintain muscle mass and bone density.
- Mood and energy: It can contribute to balanced mood, higher energy levels, and overall vitality.
- Sexual function: It’s key to maintaining libido and proper sexual performance.
When testosterone levels drop—as often happens with aging—men may experience symptoms like fatigue, loss of muscle mass, low libido, and mood changes.
TRT works by supplying your body with extra testosterone to bring these levels back up, helping to restore balance.
How TRT Works at a Cellular Level
Testosterone replacement therapy (TRT) works by adding testosterone back into the body, helping with things like muscle growth, energy, and mood. Here’s how it works inside your cells:
Testosterone Binds to Special Receptors
Once in the bloodstream, testosterone enters cells and attaches to androgen receptors—special proteins that act like “on switches” for certain body functions. (Citation)
Activating the Cell’s DNA
After binding, the receptor moves into the cell’s nucleus (the control center) and tells the DNA to turn on genes that help with things like building muscle, burning fat, and producing red blood cells.
Triggering Cell Signals for Growth
Testosterone also sends signals inside the cell that boost energy, improve strength, and support metabolism—kind of like flipping multiple switches at once to help the body function better.
The Research Behind TRT
Decades of research have shown that when testosterone is restored to normal levels, many symptoms associated with low testosterone can significantly improve.
Studies have demonstrated that TRT not only helps with physical symptoms like low energy and muscle loss but also improves mental clarity and overall quality of life.
How TRT Is Administered
TRT isn’t a one-size-fits-all treatment, and there are several ways to administer it. Here’s a look at the most common methods:
- Injections: One of the most common methods, testosterone injections are typically administered every one to two weeks. A healthcare provider will give you an injection in your muscle, and the testosterone is absorbed over time.
- Gels and creams: These are applied directly to your skin—usually on your shoulders or upper arms. The testosterone is absorbed through the skin and into your bloodstream gradually.
- Patches: Similar to gels, patches are applied to the skin and release testosterone steadily over a 24-hour period.
- Pellets: Small pellets can be implanted under the skin by a doctor, providing a steady dose of testosterone for several months.
Each method has its advantages, and some methods may not be suitable for all men.
The best option for you depends on your lifestyle, how quickly you need results, and your personal preference.
Types of Testosterone Replacement Therapy Available
There are several types of TRT available, each designed to meet different needs:
| Therapy types | How they work | Advantages | Considerations |
| Injection | Precise dose of testosterone directly into your muscle | Generally effective; adjustable based on doctor recommendations | Regular jabs required; close monitoring of T levels by doctor; injection-site discomfort |
| Gel or cream | Applied directly to the skin; T absorbed gradually over time | Noninvasive method that can be easily incorporated into daily routine | Possible transfer of testosterone to others if not dried completely |
| Patch or pellet | Consistent release of testosterone with patches; long-term, steady dosing from implanted pellets | Reduced hassle of frequent applications or injections | Minor surgical procedure to implant pellets; daily replacement of patches |
| Oral tablet | Swallowed, usually twice per day with meals | Convenient and noninvasive | Must be taken with meals twice daily; potential liver damage |
How to Take TRT
Starting TRT involves a few key steps:
- Consult with a doctor: The first step is always a consultation with a healthcare provider. They will review your symptoms, perform blood tests, and determine if TRT is right for you.
- Discuss administration options: Once it’s confirmed that TRT could be beneficial, discuss the various methods (injections, gels, patches, pellets, or oral tablets) and choose one that fits your lifestyle.
- Follow your prescription: Whether you’re self-administering injections or applying a gel, be sure to follow your doctor’s instructions closely.
- Regular monitoring: TRT isn’t set-and-forget therapy. Regular follow-ups are essential to adjust dosage and ensure your testosterone levels are maintained within a healthy range.
Cost of Testosterone Replacement Therapy
The cost of TRT can vary widely depending on several factors:
- Type of treatment: Injections are typically less expensive than gels, patches, pellets, or pills.
- Insurance coverage: Many insurance plans cover TRT if prescribed by a doctor, which can significantly reduce your out-of-pocket expenses.
- Out-of-pocket expenses: If you’re uninsured or your plan doesn’t cover TRT, monthly membership fees at online clinics generally range from $25 to $45, with additional costs for prescription medications.
Pros and Cons of Testosterone Replacement Therapy
Before starting TRT, it’s important to weigh the benefits and potential drawbacks:
| Pros | Cons |
| ✔ Enhanced energy and vitality ✔ Improved muscle mass and strength ✔ Better mood and cognitive function ✔ Increased libido and improved sexual performance ✔ Bone health | ✘ Potential side effects and risks ✘ Cost without insurance ✘ Regular monitoring ✘ Not a cure-all |
Alternatives to Testosterone Replacement Therapy
If TRT doesn’t seem like the right fit for you, there are alternatives to consider:
- Lifestyle changes: Improving your diet, getting regular exercise, and managing stress can help boost testosterone naturally. Although lifestyle changes are important, for men with clinically low testosterone, they are often not enough.
- Supplements: Certain supplements claim to support testosterone production, though their effectiveness varies. Use caution with supplements because many lack scientific evidence.
- Medications: In some cases, other medications might be recommended to address symptoms associated with low testosterone.
- Therapy and counseling: If low testosterone is affecting your mood or relationships, speaking with a counselor might help.
Each alternative has its own pros and cons, and it’s important to discuss these options with your healthcare provider.
Wrapping It Up
Navigating low testosterone and considering TRT can feel like a big decision, but getting informed is the first step to feeling better. Whether you decide to try testosterone replacement therapy or explore alternatives, the key is working closely with a trusted healthcare provider.
Online TRT clinics like FountainTRT, Defy Medical, and others offer convenient, personalized, and accessible ways to get your testosterone levels back on track.
Each clinic has its own strengths—whether it’s a rapid, streamlined process, a fully online approach that emphasizes convenience, or a balance of affordability and quality care.
By comparing their services, costs, and available treatment options, you can find the right fit for your needs and lifestyle.
FAQs
How long do you have to do testosterone replacement therapy?
How long you receive testosterone replacement therapy depends on your own circumstances. Some men use it temporarily to get through a period of low testosterone, while others continue long term, depending on their needs and how well they respond to treatment. Regular check-ins with your doctor will help determine the best duration for you.
Does testosterone therapy actually work?
Yes, testosterone therapy actually works for many men. You can see significant improvements in energy, muscle mass, mood, and sexual performance. However, results can vary, and it might take a few weeks or months to notice the full benefits.
Why are some doctors against TRT?
Some doctors are cautious about TRT because of potential risks, like cardiovascular or liver issues or other side effects. That’s why it’s important to have a thorough consultation and follow-up with your healthcare provider to ensure the benefits outweigh the risks for you.
Does TRT cause weight gain?
No, TRT itself doesn’t directly cause weight gain, but it can lead to an increase in muscle mass, which might slightly change your body composition. When combined with a healthy lifestyle, TRT can help you manage weight more effectively.
What are signs of low testosterone?
Signs of low testosterone include low energy, reduced muscle mass, increased body fat, mood changes, decreased libido, and cognitive difficulties. If you’re experiencing several of these symptoms, it might be time to discuss TRT with your doctor.
What are signs that TRT is not working?
Signs that TRT is not working include sustained fatigue and no improvement in strength or mood, as well as new signs of low testosterone. However, these might just be signs that your TRT dosage needs adjustment or that another treatment might be necessary. Regular monitoring is key.
Does insurance cover TRT?
Many insurance plans do cover TRT when prescribed by a doctor. Coverage details can vary, so it’s important to check with your provider to see if your plan includes TRT services.
How long does it take TRT to start helping symptoms?
How long it takes for TRT to start helping depends on each individual man and his treatment protocol. However, most men taking TRT start to notice improvements within a few weeks to a couple of months.
Where can I find more information about studies related to TRT?
You can learn more about TRT studies from these websites:
This article is for informational purposes only and should not replace professional medical advice. Always consult your healthcare provider before starting any new treatment.